Journal article
Tracing Environmental Exposure from Neurodevelopment to Neurodegeneration
AL Heffernan, DJ Hare
Trends in Neurosciences | ELSEVIER SCIENCE LONDON | Published : 2018
Abstract
Interplay between genetic and environmental factors during critical time windows can have effects that span from neurodevelopment to neurodegeneration. We present the concept of the ‘neuroexposome’ emphasizing the brain's distinctive response to environmental exposure, and how current ‘omics’ sciences can inform on both disease pathogenesis and future public health policies.
Grants
Awarded by Institute of Neurosciences, Mental Health and Addiction
Funding Acknowledgements
This work was supported by a joint National Health and Medical Research Council/Australian Research Council Dementia Research Development Fellowship (A.L.H.; 1106911) and a National Health and Medical Research Council Industry Career Development Fellowship (D.J.H.; 1122981). D.J.H. receives research and material support from Agilent Technologies. The authors wish to acknowledge the support provided to The Florey Institute of Neuroscience and Mental Health from the Victorian Government Operational Infrastructure Support Program.